UFM1

Protein

About

Thing
Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene. UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1.
UFM1
Definition
Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene. UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1.
UFM1
UFM1
Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene. UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1.

Mentions

The authors designed a genome-wide CRISPR–Cas9 screen to identify factors that are upregulated or downregulated during ER-phagy induced by starvation (the only currently known cue for ER-phagy induction). The screen returned 200 high-confidence genes, which coalesced into several functional groups, including ‘predictable’ factors, such as general autophagy mediators, components of secretory pathways and regulators of ER homeostasis and stress. Less expectedly, among the genes most highly associated with ER-phagy disruption were those linked to mitochondrial oxidative metabolism, specifically oxidative phosphorylation (OXPHOS) and those implicated in UFMylation, which involves the transfer of the ubiquitin-like protein ubiquitin-fold modifier 1 (UFM1) onto Lys residues by the E1 enzyme UBA5, by the E2 enzyme UFC1 and by E3 UFM1-protein ligase 1 (UFL1).

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В морфемном словаре русского языка МОРФЕМА.РУС приведен разбор слов по составу (морфемный разбор, морфемный анализ). Даный словарь поможет в проведении морфемного анализа не только начальных (словарных) форм слов, но и всех их словоформ (всех грамматических форм слов русского языка). В основу морфемного словаря "Морфема" положена наиболее полная лексика русского языка.

Разбор слов по составу (морфемный анализ) с выделением корня, суффикса, основы и окончания: "снова", "помощник", "вдали", "преспокойно", "упорно", "досыта", "беспредельный", "тотчас", "радость", "скоро".

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