Discovered and developed by AbbVie, RINVOQ is a selective and reversible JAK inhibitor studied in several immune-mediated inflammatory diseases. In August 2019, RINVOQ received U.S. Food and Drug Administration approval for adult patients with moderately to severely active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate. In December 2019, RINVOQ also received approval by the European Commission for the treatment of adult patients with moderate to severe active rheumatoid arthritis who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs. Phase 3 trials of RINVOQ in rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis, Crohn's disease, atopic dermatitis, ulcerative colitis and giant cell arteritis are ongoing.
The Scottish Funding Council said this week that a country-wide precision medicine initiative in Scotland has received up to £9.5 million ($12.3 million) in new funding. The funding includes £7.5 million from the council and up to £2 million from Scottish Enterprise, and will support the growth of precision medicine in Scotland managed by the Precision Medicine Scotland Innovation Centre (formerly the Stratified Medicine Scotland Innovation Centre). The newly launched phase 2 of the center will continue to act as a catalyst for partnerships between industry, academia, and clinical entities. In phase 1 the Innovation Centre produced several large-scale projects in areas including ovarian cancer, rheumatoid arthritis, esophageal cancer, and multiple sclerosis. The center said it expects to be able to attract around £4.2 million in income from other sources.