The program will aim to develop and evaluate next-generation genomics and informatics tools to improve the diagnosis, treatment, and prevention of disease. It will leverage available tools and recent research in genomic technologies, computation, and data science, as well as large genomic datasets, DNA from hundreds of thousands of participants collected and stored in biobanks, and electronic health records.
Comparing a patient’s DNA to reference data will allow doctors to find other people with similar DNA variants and see how they were diagnosed and treated. SolveBio’s founding team is currently focused on building a system that can integrate genomics data into diagnostic and research applications, which it will make available as an API.
“Genomics has the potential to dramatically improve patient care in oncology, but the full promise of precision medicine cannot be realized without a software platform to bring genomics to the point of care,” said Jonathan Hirsch, who founded Syapse six years ago as a 23-year-old Stanford University graduate student. “It is critical that genomic data be integrated with the patient’s medical history and presented to the clinician within the workflow of their EMR.”
“At the time there was a lot of discomfort around the marrying of software and genomics,” says Mangubat, a member of Forbes’ 30 Under 30 list for Science and Healthcare in 2012. It was difficult to find investors with expertise in both areas, she says, or one who was willing to make a bet in an sector they didn’t understand. Spiral Genetics raised $5 million in venture capital before genomic data software firm Omicia, now Fabric Genomics, bought it in 2017 for an undisclosed amount.
Portfolia launched the first ever Femtech focused investment fund in 2017, and has since invested in fertility company Future Family, vaginal health startup Madorra, genomics and diagnostics company Prime Genomics, which is developing a breakthrough approach to detect cancer, and the newest addition, Sana, an innovative device for pain management. Additionally, Portfolia has invested through others funds on menopause health platform Genneve and device company Joylux. Christina Jenkins, MD, is also an independent advisor to Elektra Health, a startup focusing on guiding women through menopause launching in 2020.
OnRamp Bioinformatics, Inc., a genomics company providing the premier scientist-focused data analysis platform, and Advaita BioInformatics, a leader in personalized medicine and interpretation of Next-Gen Sequencing data, announced they have partnered to provide a comprehensive research experience from sample to interpretation with a seamless hand-off between systems.